RG3/Synapsin is a physician-prescribed nasal spray designed to support memory, focus, and neurological resilience. At Blue Zone Clinic’s, we use cutting-edge regenerative therapies to help you stay sharp, energized, and performing at your best.
RG3/Synapsin is a compounded nasal spray that combines ginsenoside Rg3 (an active compound from ginseng) with nicotinamide riboside (a precursor to NAD+). Together, these ingredients promote healthy neurological function, cognitive performance, and mitochondrial energy production.
Originally studied for brain injury recovery and neuroinflammation, RG3/Synapsin is now used off-label as a performance-enhancing nootropic and neuroprotective therapy for long-term brain optimization.

Meet 1:1 with a licensed healthcare provider specializing in longevity and regenerative health. Your provider will evaluate your health history, symptoms, and goals to determine if Metformin is right for you.

If prescribed, your treatment will be shipped directly to your door from a licensed pharmacy partner.

We’ll check in regularly and adjust your care plan as needed for optimal results.
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Most patients use 1 spray per nostril 1-2x daily, depending on provider recommendation.
Cognitive benefits may be noticeable within 1 to 2 weeks of regular use.
Yes. To preserve potency, keep your bottle refrigerated between uses.
Yes. Synapsin can complement other Blue Zone longevity therapies.
Side effects are rare and generally mild. Always follow your provider's guidance.
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*If you are interested in a prescription product, AgelessRx will assist in setting up a visit for you with a licensed medical professional, who will evaluate whether or not you are an appropriate candidate for the prescription product. If appropriate, he/she may write you a prescription for the product which is fulfilled at a partnering pharmacy, unless requested otherwise.